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Bacteria-driven hypoxia targeting delivery of chemotherapeutic drug proving outcome of breast cancer

Local hypoxia is a common feature of many solid tumors and may lead to unsatisfactory chemotherapy outcomes. Anaerobic bacteria that have an affinity to hypoxic areas can be used to achieve targeted drug delivery in tumor tissues. In this study, we developed a biocompatible bacteria/nanoparticles bi...

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Detalles Bibliográficos
Autores principales: Xiao, Susu, Shi, Huan, Zhang, Yan, Fan, Yu, Wang, Li, Xiang, Li, Liu, Yanlin, Zhao, Ling, Fu, Shaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976953/
https://www.ncbi.nlm.nih.gov/pubmed/35366890
http://dx.doi.org/10.1186/s12951-022-01373-1