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Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful use of vitamin D (1,25VD3) gene therapy to treat AML mouse...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Hino, Christopher, Baylink, David J., Xiao, Jeffrey, Reeves, Mark E., Zhong, Jiang F., Mirshahidi, Saied, Cao, Huynh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977002/
https://www.ncbi.nlm.nih.gov/pubmed/35366947
http://dx.doi.org/10.1186/s40364-022-00367-3