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Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia
Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful use of vitamin D (1,25VD3) gene therapy to treat AML mouse...
Autores principales: | Xu, Yi, Hino, Christopher, Baylink, David J., Xiao, Jeffrey, Reeves, Mark E., Zhong, Jiang F., Mirshahidi, Saied, Cao, Huynh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977002/ https://www.ncbi.nlm.nih.gov/pubmed/35366947 http://dx.doi.org/10.1186/s40364-022-00367-3 |
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