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Amphipathic dendritic poly-peptides carrier to deliver antisense oligonucleotides against multi-drug resistant bacteria in vitro and in vivo

BACKGROUND: Outbreaks of infection due to multidrug-resistant (MDR) bacteria, especially Gram-negative bacteria, have become a global health issue in both hospitals and communities. Antisense oligonucleotides (ASOs) based therapeutics hold a great promise for treating infections caused by MDR bacter...

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Detalles Bibliográficos
Autores principales: Chen, Zhou, Hu, Yue, Mao, Xinggang, Nie, Dan, Zhao, Hui, Hou, Zheng, Li, Mingkai, Meng, Jingru, Luo, Xiaoxing, Xue, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977034/
https://www.ncbi.nlm.nih.gov/pubmed/35366899
http://dx.doi.org/10.1186/s12951-022-01384-y