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Divergent G-protein selectivity across melanopsins from mice and humans
Melanopsin is an opsin photopigment and light-activated G-protein-coupled receptor; it is expressed in photoreceptive retinal ganglion cells (mRGCs) and can be employed as an optogenetic tool. Mammalian melanopsins can signal via G(q/11) and G(i/o/t) heterotrimeric G proteins, but aspects of the mRG...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977054/ https://www.ncbi.nlm.nih.gov/pubmed/35274137 http://dx.doi.org/10.1242/jcs.258474 |