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Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells

Liver cancers, including hepatocellular carcinoma (HCC), are the second leading cause of cancer death worldwide, and novel therapeutic strategies are still highly needed. Recently, the endolysosomal cation channel TRPML1 (also known as MCOLN1) has gained focus in cancer research because it represent...

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Detalles Bibliográficos
Autores principales: Siow, Wei Xiong, Kabiri, Yaschar, Tang, Rachel, Chao, Yu-Kai, Plesch, Eva, Eberhagen, Carola, Flenkenthaler, Florian, Fröhlich, Thomas, Bracher, Franz, Grimm, Christian, Biel, Martin, Zischka, Hans, Vollmar, Angelika M., Bartel, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977057/
https://www.ncbi.nlm.nih.gov/pubmed/35274126
http://dx.doi.org/10.1242/jcs.259455