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The prophase oocyte nucleus is a homeostatic G-actin buffer

Formation of healthy mammalian eggs from oocytes requires specialised F-actin structures. F-actin disruption produces aneuploid eggs, which are a leading cause of human embryo deaths, genetic disorders and infertility. We found that oocytes contain prominent nuclear F-actin structures that are corre...

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Detalles Bibliográficos
Autores principales: Scheffler, Kathleen, Giannini, Federica, Lemonnier, Tom, Mogessie, Binyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977058/
https://www.ncbi.nlm.nih.gov/pubmed/35112707
http://dx.doi.org/10.1242/jcs.259807