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Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS

PURPOSE: Acute lung injury (ALI) is a life-threatening condition with limited therapeutic options. Macrophage inflammation plays a key role in the development of ALI. Abnormal glycolysis of macrophages contributes to the inflammatory response. However, the role of macrophage glycolysis in ALI still...

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Detalles Bibliográficos
Autores principales: Yuan, Yafei, Wang, Wei, Zhang, Yue, Hong, Qiaohui, Huang, Wenhui, Li, Lijuan, Xie, Zhanzhan, Chen, Yixin, Li, Xu, Meng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977227/
https://www.ncbi.nlm.nih.gov/pubmed/35386222
http://dx.doi.org/10.2147/JIR.S348850