Cargando…

Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS

PURPOSE: Acute lung injury (ALI) is a life-threatening condition with limited therapeutic options. Macrophage inflammation plays a key role in the development of ALI. Abnormal glycolysis of macrophages contributes to the inflammatory response. However, the role of macrophage glycolysis in ALI still...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Yafei, Wang, Wei, Zhang, Yue, Hong, Qiaohui, Huang, Wenhui, Li, Lijuan, Xie, Zhanzhan, Chen, Yixin, Li, Xu, Meng, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977227/ https://www.ncbi.nlm.nih.gov/pubmed/35386222 http://dx.doi.org/10.2147/JIR.S348850

Ejemplares similares

Role of PFKFB3-driven glycolysis in sepsis
por: Xiao, Min, et al.
Publicado: (2023)

Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy
por: Wang, Wei, et al.
Publicado: (2023)

Fc-apelin fusion protein attenuates lipopolysaccharide-induced liver injury in mice
por: Zhou, Huifen, et al.
Publicado: (2018)

Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis
por: Chen, Weimou, et al.
Publicado: (2021)

Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response
por: Zeng, Hao, et al.
Publicado: (2022)

NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma
por: Su, Xiangsheng, et al.
Publicado: (2021)

Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway
por: Li, Jiameng, et al.
Publicado: (2021)

Suppression of myeloid PFKFB3‐driven glycolysis protects mice from choroidal neovascularization
por: Liu, Zhiping, et al.
Publicado: (2022)

NOX- and ROS-Driven Hypertension in Elastin Insufficiency
por: Gavazzi, Gaëtan, et al.
Publicado: (2021)

HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression
por: Wang, Yixin, et al.
Publicado: (2021)

Author Correction: Fc-apelin fusion protein attenuates lipopolysaccharide-induced liver injury in mice
por: Zhou, Huifen, et al.
Publicado: (2018)

Statins attenuate cholesterol-induced ROS via inhibiting NOX2/NOX4 and mitochondrial pathway in collecting ducts of the kidney
por: Wang, Ani, et al.
Publicado: (2022)

NOX4-derived ROS Regulates Aerobic Glycolysis of Breast Cancer through YAP Pathway
por: Zhang, Zhenzhen, et al.
Publicado: (2023)

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
por: Zhang, Xinhua, et al.
Publicado: (2022)

Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury
por: Sun, Dandan, et al.
Publicado: (2022)

Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
por: Yang, Qiuhua, et al.
Publicado: (2023)

Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis
por: Li, Fu-Long, et al.
Publicado: (2018)

Correction: Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS
Publicado: (2021)

Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma
por: Li, Jun, et al.
Publicado: (2022)

Mir‐488 alleviates chemoresistance and glycolysis of colorectal cancer by targeting PFKFB3
por: Deng, Xiaojing, et al.
Publicado: (2020)

PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb
por: Ryan, Terence E., et al.
Publicado: (2020)

Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
por: Yang, Kaiying, et al.
Publicado: (2023)

miR-1297 Suppresses Osteosarcoma Proliferation and Aerobic Glycolysis by Regulating PFKFB2
por: Pan, Xiaohui, et al.
Publicado: (2020)

Expression of Concern: Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS
Publicado: (2020)

Involvement of PFKFB3 in Pulmonary Arterial Hypertension Pathogenesis. Is It All about Glycolysis?
por: Bonnet, Sebastien, et al.
Publicado: (2019)

The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition
por: Emini Veseli, Besa, et al.
Publicado: (2021)

PFKFB3-Mediated Glycolysis Boosts Fibroblast Activation and Subsequent Kidney Fibrosis
por: Yang, Qiuhua, et al.
Publicado: (2023)

Oridonin Attenuates Lipopolysaccharide-Induced ROS Accumulation and Inflammation in HK-2 Cells
por: Huang, Jen-Hsuan, et al.
Publicado: (2020)

Effect and mechanism of apelin on lipopolysaccharide induced acute pulmonary vascular endothelial barrier dysfunction
por: Huang, Tianpeng, et al.
Publicado: (2023)

AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway
por: Chen, Ying-Hua, et al.
Publicado: (2018)

Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth
por: Hu, Jiahao, et al.
Publicado: (2022)

Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
por: Lu, Chao, et al.
Publicado: (2022)

MicroRNA‐488 inhibits proliferation and glycolysis in human prostate cancer cells by regulating PFKFB3
por: Wang, Jun, et al.
Publicado: (2019)

The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice
por: Cui, Yu, et al.
Publicado: (2018)

Inactivation of Adenosine A(2A) Receptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial Cells
por: Thakur, Sapna, et al.
Publicado: (2010)

Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS
por: Ligtenberg, Maarten A., et al.
Publicado: (2015)

Attenuated NOX2 expression impairs ROS production during the hypoinflammatory phase of sepsis
por: Kuchler, L, et al.
Publicado: (2012)

Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration
por: Rodriguez-Rodriguez, P, et al.
Publicado: (2012)

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer
por: Lu, Chao, et al.
Publicado: (2021)

Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation
por: Zhou, Zhou, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u83et70v8co06m44kam9h9pact