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The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a serine/threonine kinase that belongs to the DYRK family of proteins, a subgroup of the evolutionarily conserved CMGC protein kinase superfamily. Due to its localization on chromosome 21, the biological significance of DYRK1A...

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Detalles Bibliográficos
Autores principales: Rammohan, Malini, Harris, Ethan, Bhansali, Rahul S., Zhao, Emily, Li, Loretta S., Crispino, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977259/
https://www.ncbi.nlm.nih.gov/pubmed/35220406
http://dx.doi.org/10.1038/s41388-022-02245-6