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The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a serine/threonine kinase that belongs to the DYRK family of proteins, a subgroup of the evolutionarily conserved CMGC protein kinase superfamily. Due to its localization on chromosome 21, the biological significance of DYRK1A...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977259/ https://www.ncbi.nlm.nih.gov/pubmed/35220406 http://dx.doi.org/10.1038/s41388-022-02245-6 |