Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation

β cell dysfunction is the leading cause of diabetes. Adult β cells have matured glucose-stimulated insulin secretion (GSIS), whereas fetal and neonatal β cells are insensitive to glucose and are functionally immature. However, how β cells mature and acquire robust GSIS is not fully understood. Here,...

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Detalles Bibliográficos
Autores principales: Lu, Li, Zhitao, Li, Nannan, Cui, Mingzhu, Huang, Xiaoping, Hu, Dongsheng, Hong, Zongfu, Pan, Xiaoyang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977338/
https://www.ncbi.nlm.nih.gov/pubmed/35386849
http://dx.doi.org/10.1155/2022/1172795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977338/
https://www.ncbi.nlm.nih.gov/pubmed/35386849
http://dx.doi.org/10.1155/2022/1172795

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