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Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation

β cell dysfunction is the leading cause of diabetes. Adult β cells have matured glucose-stimulated insulin secretion (GSIS), whereas fetal and neonatal β cells are insensitive to glucose and are functionally immature. However, how β cells mature and acquire robust GSIS is not fully understood. Here,...

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Detalles Bibliográficos
Autores principales:	Lu, Li, Zhitao, Li, Nannan, Cui, Mingzhu, Huang, Xiaoping, Hu, Dongsheng, Hong, Zongfu, Pan, Xiaoyang, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977338/ https://www.ncbi.nlm.nih.gov/pubmed/35386849 http://dx.doi.org/10.1155/2022/1172795

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