Maintenance of Sertoli Cell Number and Function in Immature Human Testicular Tissues Exposed to Platinum-Based Chemotherapy—Implications for Fertility Restoration

Background: Retrospective studies in adult survivors of childhood cancer show long-term impacts of exposure to alkylating chemotherapy on future fertility. We recently demonstrated germ cell loss in immature human testicular tissues following exposure to platinum-based chemotherapeutic drugs. This s...

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Detalles Bibliográficos
Autores principales: Matilionyte, Gabriele, Tharmalingam, Melissa D., Sanou, Iris, Lopes, Federica, Lane, Sheila, Stukenborg, Jan-Bernd, Spears, Norah, Anderson, Richard A., Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977418/
https://www.ncbi.nlm.nih.gov/pubmed/35387428
http://dx.doi.org/10.3389/ftox.2022.825734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977418/
https://www.ncbi.nlm.nih.gov/pubmed/35387428
http://dx.doi.org/10.3389/ftox.2022.825734

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