Cargando…
Maintenance of Sertoli Cell Number and Function in Immature Human Testicular Tissues Exposed to Platinum-Based Chemotherapy—Implications for Fertility Restoration
Background: Retrospective studies in adult survivors of childhood cancer show long-term impacts of exposure to alkylating chemotherapy on future fertility. We recently demonstrated germ cell loss in immature human testicular tissues following exposure to platinum-based chemotherapeutic drugs. This s...
Autores principales: | Matilionyte, Gabriele, Tharmalingam, Melissa D., Sanou, Iris, Lopes, Federica, Lane, Sheila, Stukenborg, Jan-Bernd, Spears, Norah, Anderson, Richard A., Mitchell, Rod T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977418/ https://www.ncbi.nlm.nih.gov/pubmed/35387428 http://dx.doi.org/10.3389/ftox.2022.825734 |
Ejemplares similares
-
Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
por: Tharmalingam, Melissa D., et al.
Publicado: (2020) -
Comparative Toxicotranscriptomics of Single Cell RNA-Seq and Conventional RNA-Seq in TCDD-Exposed Testicular Tissue
por: Haimbaugh, Alex, et al.
Publicado: (2022) -
Exogenous Gonadotrophin Stimulation Induces Partial Maturation of Human Sertoli Cells in a Testicular Xenotransplantation Model for Fertility Preservation
por: Hutka, Marsida, et al.
Publicado: (2020) -
Cisplatin Effects on the Human Fetal Testis – Establishing the Sensitive Period for (Pre)Spermatogonial Loss and Relevance for Fertility Preservation in Pre-Pubertal Boys
por: Matilionyte, Gabriele, et al.
Publicado: (2022) -
Atrazine: cytotoxicity, oxidative stress, apoptosis, testicular effects and chemopreventive Interventions
por: Abarikwu, Sunny O., et al.
Publicado: (2023)