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Predicted coronavirus Nsp5 protease cleavage sites in the human proteome

BACKGROUND: The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also been found to cleave host proteins, disrupting molecular pathways involved in inna...

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Detalles Bibliográficos
Autores principales: Scott, Benjamin M., Lacasse, Vincent, Blom, Ditte G., Tonner, Peter D., Blom, Nikolaj S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977440/
https://www.ncbi.nlm.nih.gov/pubmed/35379171
http://dx.doi.org/10.1186/s12863-022-01044-y