Cargando…
Predicted coronavirus Nsp5 protease cleavage sites in the human proteome
BACKGROUND: The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also been found to cleave host proteins, disrupting molecular pathways involved in inna...
Autores principales: | Scott, Benjamin M., Lacasse, Vincent, Blom, Ditte G., Tonner, Peter D., Blom, Nikolaj S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977440/ https://www.ncbi.nlm.nih.gov/pubmed/35379171 http://dx.doi.org/10.1186/s12863-022-01044-y |
Ejemplares similares
-
Coronavirus 3CL(pro )proteinase cleavage sites: Possible relevance to SARS virus pathology
por: Kiemer, Lars, et al.
Publicado: (2004) -
Regulation of coronavirus nsp15 cleavage specificity by RNA structure
por: Salukhe, Indraneel, et al.
Publicado: (2023) -
Prediction of coronavirus 3C-like protease cleavage sites using machine-learning algorithms
por: Chen, Huiting, et al.
Publicado: (2022) -
SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
por: Huang, Cheng, et al.
Publicado: (2011) -
Ligand-induced Dimerization of Middle East Respiratory Syndrome
(MERS) Coronavirus nsp5 Protease (3CL(pro)): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS
por: Tomar, Sakshi, et al.
Publicado: (2015)