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The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism
Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs). However, it is still challenging to maintain high productivity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977551/ https://www.ncbi.nlm.nih.gov/pubmed/35387297 http://dx.doi.org/10.3389/fbioe.2022.832065 |