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The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism

Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs). However, it is still challenging to maintain high productivity...

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Detalles Bibliográficos
Autores principales: Liu, Hui-Ning, Dong, Wei-Hua, Lin, Yan, Zhang, Zhao-Hui, Wang, Tian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977551/
https://www.ncbi.nlm.nih.gov/pubmed/35387297
http://dx.doi.org/10.3389/fbioe.2022.832065