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Unsupervised Mining of HLA-I Peptidomes Reveals New Binding Motifs and Potential False Positives in the Community Database

Modern vaccine designs and studies of human leukocyte antigen (HLA)-mediated immune responses rely heavily on the knowledge of HLA allele-specific binding motifs and computational prediction of HLA-peptide binding affinity. Breakthroughs in HLA peptidomics have considerably expanded the databases of...

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Detalles Bibliográficos
Autores principales: Sricharoensuk, Chatchapon, Boonchalermvichien, Tanupat, Muanwien, Phijitra, Somparn, Poorichaya, Pisitkun, Trairak, Sriswasdi, Sira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977642/
https://www.ncbi.nlm.nih.gov/pubmed/35386688
http://dx.doi.org/10.3389/fimmu.2022.847756