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Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center

BACKGROUND: Angiosarcoma is a histologically and molecularly heterogeneous vascular neoplasm with aggressive clinical behavior. Emerging data suggests that immune checkpoint blockade (ICB) is efficacious against some angiosarcomas, particularly cutaneous angiosarcoma of the head and neck (CHN). METH...

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Detalles Bibliográficos
Autores principales: Rosenbaum, Evan, Antonescu, Cristina R, Smith, Shaleigh, Bradic, Martina, Kashani, Daniel, Richards, Allison L, Donoghue, Mark, Kelly, Ciara M, Nacev, Benjamin, Chan, Jason E, Chi, Ping, Dickson, Mark A, Keohan, Mary L, Gounder, Mrinal M, Movva, Sujana, Avutu, Viswatej, Thornton, Katherine, Zehir, Ahmet, Bowman, Anita S, Singer, Samuel, Tap, William, D’Angelo, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977792/
https://www.ncbi.nlm.nih.gov/pubmed/35365586
http://dx.doi.org/10.1136/jitc-2021-004149