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MSC Transplantation Attenuates Inflammation, Prevents Endothelial Damage and Enhances the Angiogenic Potency of Endogenous MSCs in a Model of Pulmonary Arterial Hypertension

PURPOSE: Pulmonary arterial hypertension (PAH) is a progressive and fatal pulmonary vascular disease initiated by endothelial dysfunction. Mesenchymal stromal cells (MSCs) have been shown to ameliorate PAH in various rodent models; however, these models do not recapitulate all the histopathological...

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Detalles Bibliográficos
Autores principales: Shao, Fengjin, Liu, Rui, Tan, Xun, Zhang, Qiaoyan, Ye, Lujie, Yan, Bingxuan, Zhuang, Ying, Xu, Jiaxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977867/
https://www.ncbi.nlm.nih.gov/pubmed/35386223
http://dx.doi.org/10.2147/JIR.S355479