Fibrinogen Mitigates Prion-Mediated Platelet Activation and Neuronal Cell Toxicity

Prion peptide (PrP) misfolds to infectious scrapie isoform, the β pleat-rich insoluble fibrils responsible for neurodegeneration and fatal conformational diseases in humans. The amino acid sequence 106–126 from prion proteins, PrP(106–126), is highly amyloidogenic and implicated in prion-induced pat...

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Detalles Bibliográficos
Autores principales: Gautam, Deepa, Kailashiya, Jyotsna, Tiwari, Arundhati, Chaurasia, Rameshwar Nath, Annarapu, Gowtham K., Guchhait, Prasenjit, Dash, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977893/
https://www.ncbi.nlm.nih.gov/pubmed/35386203
http://dx.doi.org/10.3389/fcell.2022.834016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977893/
https://www.ncbi.nlm.nih.gov/pubmed/35386203
http://dx.doi.org/10.3389/fcell.2022.834016

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