RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy

BACKGROUND: The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so far. Our...

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Detalles Bibliográficos
Autores principales: Fernández‐Simón, Esther, Suárez‐Calvet, Xavier, Carrasco‐Rozas, Ana, Piñol‐Jurado, Patricia, López‐Fernández, Susana, Pons, Gemma, Bech Serra, Joan Josep, de la Torre, Carolina, de Luna, Noemí, Gallardo, Eduard, Díaz‐Manera, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977967/
https://www.ncbi.nlm.nih.gov/pubmed/35132805
http://dx.doi.org/10.1002/jcsm.12923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977967/
https://www.ncbi.nlm.nih.gov/pubmed/35132805
http://dx.doi.org/10.1002/jcsm.12923

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