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RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy
BACKGROUND: The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so far. Our...
Autores principales: | Fernández‐Simón, Esther, Suárez‐Calvet, Xavier, Carrasco‐Rozas, Ana, Piñol‐Jurado, Patricia, López‐Fernández, Susana, Pons, Gemma, Bech Serra, Joan Josep, de la Torre, Carolina, de Luna, Noemí, Gallardo, Eduard, Díaz‐Manera, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977967/ https://www.ncbi.nlm.nih.gov/pubmed/35132805 http://dx.doi.org/10.1002/jcsm.12923 |
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