Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators

BACKGROUND: Nicotinamide phosphoribosyltransferase (Nampt), a key enzyme in NAD salvage pathway is decreased in metabolic diseases, and its precise role in skeletal muscle function is not known. We tested the hypothesis, Nampt activation by P7C3 (3,6‐dibromo‐α‐[(phenylamino)methyl]‐9H‐carbazol‐9‐eth...

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Detalles Bibliográficos
Autores principales: Manickam, Ravikumar, Tur, Jared, Badole, Sachin L., Chapalamadugu, Kalyan C., Sinha, Puja, Wang, Zhiying, Russ, David W., Brotto, Marco, Tipparaju, Srinivas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977983/
https://www.ncbi.nlm.nih.gov/pubmed/35060352
http://dx.doi.org/10.1002/jcsm.12887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977983/
https://www.ncbi.nlm.nih.gov/pubmed/35060352
http://dx.doi.org/10.1002/jcsm.12887

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