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Phase Resolution of Heterozygous Sites in Diploid Genomes is Important to Phylogenomic Analysis under the Multispecies Coalescent Model

Genome sequencing projects routinely generate haploid consensus sequences from diploid genomes, which are effectively chimeric sequences with the phase at heterozygous sites resolved at random. The impact of phasing errors on phylogenomic analyses under the multispecies coalescent (MSC) model is lar...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Bennett, Jeremy, Flouri, Tomáš, Leaché, Adam D, Yang, Ziheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977997/
https://www.ncbi.nlm.nih.gov/pubmed/34143216
http://dx.doi.org/10.1093/sysbio/syab047