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m(6)A demethylase ALKBH5 drives denervation‐induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling
BACKGROUND: Skeletal muscle atrophy is a common clinical manifestation of various neurotrauma and neurological diseases. In addition to the treatment of primary neuropathies, it is a clinical condition that should be investigated. FoxO3 activation is an indispensable mechanism in denervation‐induced...
Autores principales: | Liu, Yuantong, Zhou, Tianjian, Wang, Qinghe, Fu, Runhan, Zhang, Zengfu, Chen, Nandi, Li, Zhizhong, Gao, Guoyong, Peng, Songlin, Yang, Dazhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978003/ https://www.ncbi.nlm.nih.gov/pubmed/35142084 http://dx.doi.org/10.1002/jcsm.12929 |
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