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The Mirasol Evaluation of Reduction in Infections Trial (MERIT): study protocol for a randomized controlled clinical trial

BACKGROUND: Transfusion-transmitted infections (TTIs) are a global health challenge. One new approach to reduce TTIs is the use of pathogen reduction technology (PRT). In vitro, Mirasol PRT reduces the infectious load in whole blood (WB) by at least 99%. However, there are limited in vivo data on th...

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Detalles Bibliográficos
Autores principales: Kasirye, Ronnie, Hume, Heather A., Bloch, Evan M., Lubega, Irene, Kyeyune, Dorothy, Shrestha, Ruchee, Ddungu, Henry, Musana, Hellen Wambongo, Dhabangi, Aggrey, Ouma, Joseph, Eroju, Priscilla, de Lange, Telsa, Tartakovsky, Michael, White, Jodie L., Kakura, Ceasar, Fowler, Mary Glenn, Musoke, Philippa, Nolan, Monica, Grabowski, M. Kate, Moulton, Lawrence H., Stramer, Susan L., Whitby, Denise, Zimmerman, Peter A., Wabwire, Deo, Kajja, Isaac, McCullough, Jeffrey, Goodrich, Raymond, Quinn, Thomas C., Cortes, Robert, Ness, Paul M., Tobian, Aaron A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978156/
https://www.ncbi.nlm.nih.gov/pubmed/35379302
http://dx.doi.org/10.1186/s13063-022-06137-8