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Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability edema in patients with moderate to severe ARDS in a randomized, placebo-controlled, double-blind trial: preliminary evaluation of safety and feasibility in light of the COVID-19 pandemic

BACKGROUND: In May 2018, the first patient was enrolled in the phase-IIb clinical trial “Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Edema in Patients with Moderate to Severe ARDS.” With the onset of the COVID-19 pandemic in ear...

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Detalles Bibliográficos
Autores principales: Schmid, Benedikt, Kranke, Peter, Lucas, Rudolf, Meybohm, Patrick, Zwissler, Bernhard, Frank, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978157/
https://www.ncbi.nlm.nih.gov/pubmed/35379296
http://dx.doi.org/10.1186/s13063-022-06182-3