Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivir

Pimodivir exerts an antiviral effect on the early stages of influenza A virus replication by inhibiting the cap-binding function of polymerase basic protein 2 (PB2). In this study, we used a combination of sequence analysis and phenotypic methods to evaluate pimodivir susceptibility of influenza A v...

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Detalles Bibliográficos
Autores principales: Patel, Mira C., Chesnokov, Anton, Jones, Joyce, Mishin, Vasiliy P., De La Cruz, Juan A., Nguyen, Ha T., Zanders, Natosha, Wentworth, David E., Davis, Todd C., Gubareva, Larisa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978222/
https://www.ncbi.nlm.nih.gov/pubmed/33581212
http://dx.doi.org/10.1016/j.antiviral.2021.105035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978222/
https://www.ncbi.nlm.nih.gov/pubmed/33581212
http://dx.doi.org/10.1016/j.antiviral.2021.105035

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