Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype

Tissue factor (TF) is crucial for embryogenesis, as mice lacking TF are embryonically lethal (E10.5). This lethality may be attributed to defects in vascular development and circulatory failure, suggesting additional roles for TF in embryonic development beyond coagulation. In this study, we charact...

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Detalles Bibliográficos
Autores principales: Subramaniam, Saravanan, Liu, Jiandong, Fletcher, Craig, Ramchandran, Ramani, Weiler, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978257/
https://www.ncbi.nlm.nih.gov/pubmed/35386206
http://dx.doi.org/10.3389/fcell.2022.852989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978257/
https://www.ncbi.nlm.nih.gov/pubmed/35386206
http://dx.doi.org/10.3389/fcell.2022.852989

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