Elaiophylin Inhibits Tumorigenesis of Human Uveal Melanoma by Suppressing Mitophagy and Inducing Oxidative Stress via Modulating SIRT1/FoxO3a Signaling

Uveal melanoma (UM) is the most common primary intraocular tumor in adults, which is associated with poor prognosis. Up to 50% of UM patients develop metastasis. Therapeutics that have proven effective in cutaneous melanoma have little success in treating UM, possibly due to its low mutational burde...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xue, Zou, Wenjun, Meng, Xinmin, Ji, Jiali, Wang, Xun, Shu, Hong, Chen, Yuan, Pan, Donghui, Wang, Ke, Zhou, Fanfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978265/
https://www.ncbi.nlm.nih.gov/pubmed/35387119
http://dx.doi.org/10.3389/fonc.2022.788496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978265/
https://www.ncbi.nlm.nih.gov/pubmed/35387119
http://dx.doi.org/10.3389/fonc.2022.788496

Ejemplares similares