Metformin Promotes Differentiation and Attenuates H(2)O(2)-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway

At present, the drug treatment of osteoporosis is mostly focused on inhibiting osteoclastogenesis, which has relatively poor effects. Metformin is a drug that can potentially promote osteogenic differentiation and improve bone mass in postmenopausal women. We aimed to detect the molecular mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Keda, Cao, Fangming, Qiu, Shui, Jiang, Wen, Tao, Lin, Zhu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978328/
https://www.ncbi.nlm.nih.gov/pubmed/35387349
http://dx.doi.org/10.3389/fphar.2022.829830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978328/
https://www.ncbi.nlm.nih.gov/pubmed/35387349
http://dx.doi.org/10.3389/fphar.2022.829830

Ejemplares similares