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Metformin Promotes Differentiation and Attenuates H(2)O(2)-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway

At present, the drug treatment of osteoporosis is mostly focused on inhibiting osteoclastogenesis, which has relatively poor effects. Metformin is a drug that can potentially promote osteogenic differentiation and improve bone mass in postmenopausal women. We aimed to detect the molecular mechanism...

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Detalles Bibliográficos
Autores principales:	Yang, Keda, Cao, Fangming, Qiu, Shui, Jiang, Wen, Tao, Lin, Zhu, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978328/ https://www.ncbi.nlm.nih.gov/pubmed/35387349 http://dx.doi.org/10.3389/fphar.2022.829830

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