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A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets

Neoantigens are mutated antigens specifically generated by cancer cells but absent in normal cells. With high specificity and immunogenicity, neoantigens are considered as an ideal target for immunotherapy. This study was aimed to investigate the signature of neoantigens in breast cancer. Somatic mu...

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Detalles Bibliográficos
Autores principales: Zhou, Si, Liu, Songming, Zhao, Lijian, Sun, Hai-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978336/
https://www.ncbi.nlm.nih.gov/pubmed/35387130
http://dx.doi.org/10.3389/fonc.2022.786438