The contribution of evolutionarily volatile promoters to molecular phenotypes and human trait variation

BACKGROUND: Promoters are sites of transcription initiation that harbour a high concentration of phenotype-associated genetic variation. The evolutionary gain and loss of promoters between species (collectively, termed turnover) is pervasive across mammalian genomes and may play a prominent role in...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Robert S., Talmane, Lana, Marion de Procé, Sophie, Taylor, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978360/
https://www.ncbi.nlm.nih.gov/pubmed/35379293
http://dx.doi.org/10.1186/s13059-022-02634-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978360/
https://www.ncbi.nlm.nih.gov/pubmed/35379293
http://dx.doi.org/10.1186/s13059-022-02634-w

Ejemplares similares