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The contribution of evolutionarily volatile promoters to molecular phenotypes and human trait variation
BACKGROUND: Promoters are sites of transcription initiation that harbour a high concentration of phenotype-associated genetic variation. The evolutionary gain and loss of promoters between species (collectively, termed turnover) is pervasive across mammalian genomes and may play a prominent role in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978360/ https://www.ncbi.nlm.nih.gov/pubmed/35379293 http://dx.doi.org/10.1186/s13059-022-02634-w |