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Novel drug-target interactions via link prediction and network embedding

BACKGROUND: As many interactions between the chemical and genomic space remain undiscovered, computational methods able to identify potential drug-target interactions (DTIs) are employed to accelerate drug discovery and reduce the required cost. Predicting new DTIs can leverage drug repurposing by i...

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Detalles Bibliográficos
Autores principales: Amiri Souri, E., Laddach, R., Karagiannis, S. N., Papageorgiou, L. G., Tsoka, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978405/
https://www.ncbi.nlm.nih.gov/pubmed/35379165
http://dx.doi.org/10.1186/s12859-022-04650-w