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Probabilistic modeling methods for cell-free DNA methylation based cancer classification

BACKGROUND: cfMeDIP-seq is a low-cost method for determining the DNA methylation status of cell-free DNA and it has been successfully combined with statistical methods for accurate cancer diagnostics. We investigate the diagnostic classification aspect by applying statistical tests and dimension red...

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Detalles Bibliográficos
Autores principales: Halla-aho, Viivi, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978416/
https://www.ncbi.nlm.nih.gov/pubmed/35379172
http://dx.doi.org/10.1186/s12859-022-04651-9