JNK‐mediated Ser27 phosphorylation and stabilization of SIRT1 promote growth and progression of colon cancer through deacetylation‐dependent activation of Snail

Sirtuin 1 (SIRT1), an NAD(+)‐dependent histone/protein deacetylase, has multifaceted functions in various biological events such as inflammation, aging, and energy metabolism. The role of SIRT1 in carcinogenesis, however, is still under debate. Recent studies have indicated that aberrant overexpress...

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Detalles Bibliográficos
Autores principales: Lee, Yeon‐Hwa, Kim, Su‐Jung, Fang, Xizhu, Song, Na‐Young, Kim, Do‐Hee, Suh, Jinyoung, Na, Hye‐Kyung, Kim, Kyung‐Ok, Baek, Jeong‐Heum, Surh, Young‐Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978515/
https://www.ncbi.nlm.nih.gov/pubmed/34826187
http://dx.doi.org/10.1002/1878-0261.13143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978515/
https://www.ncbi.nlm.nih.gov/pubmed/34826187
http://dx.doi.org/10.1002/1878-0261.13143

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