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Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis

Immune checkpoint inhibitors (ICIs) are widely used to treat various malignancies. Although the gut microbiome is known to influence the efficacy of ICIs on epithelial tumors, the functional interactions between gut taxa and colonic mucosa remain poorly understood. Here we performed transcriptomic p...

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Detalles Bibliográficos
Autores principales: Sakurai, Toshiharu, De Velasco, Marco A, Sakai, Kazuko, Nagai, Tomoyuki, Nishiyama, Hiroki, Hashimoto, Kentaro, Uemura, Hirotsugu, Kawakami, Hisato, Nakagawa, Kazuhiko, Ogata, Hiroyuki, Nishio, Kazuto, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978521/
https://www.ncbi.nlm.nih.gov/pubmed/34270845
http://dx.doi.org/10.1002/1878-0261.13062