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Hypothalamic Nesfatin-1 Resistance May Underlie the Development of Type 2 Diabetes Mellitus in Maternally Undernourished Non-obese Rats

Intrauterine growth retardation (IUGR) poses a high risk for developing late-onset, non-obese type 2 diabetes (T2DM). The exact mechanism underlying this phenomenon is unknown, although the contribution of the central nervous system is recognized. The main hypothalamic nuclei involved in the homeost...

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Detalles Bibliográficos
Autores principales: Durst, Máté, Könczöl, Katalin, Ocskay, Klementina, Sípos, Klaudia, Várnai, Péter, Szilvásy-Szabó, Anett, Fekete, Csaba, Tóth, Zsuzsanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978526/
https://www.ncbi.nlm.nih.gov/pubmed/35386592
http://dx.doi.org/10.3389/fnins.2022.828571