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Apolar chemical environments compact unfolded RNAs and can promote folding

It is well documented that the structure, and thus function, of nucleic acids depends on the chemical environment surrounding them, which often includes potential proteinaceous binding partners. The nonpolar amino acid side chains of these proteins will invariably alter the polarity of the local che...

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Detalles Bibliográficos
Autores principales: Gunawardhana, Shamal M., Holmstrom, Erik D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978554/
https://www.ncbi.nlm.nih.gov/pubmed/35382036
http://dx.doi.org/10.1016/j.bpr.2021.100004