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Molecular Mechanism Underlying Effects of Wumeiwan on Steroid-Dependent Asthma: A Network Pharmacology, Molecular Docking, and Experimental Verification Study

BACKGROUND: Steroid-dependent asthma (SDA) is characterized by oral corticosteroid (OCS) resistance and dependence. Wumeiwan (WMW) showed potentials in reducing the dose of OCS of SDA patients based on our previous studies. METHODS: Network pharmacology was conducted to explore the molecular mechani...

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Detalles Bibliográficos
Autores principales: Lyu, Mingsheng, Wang, Yahui, Chen, Qiuyi, Qin, Jingbo, Hou, Dan, Huang, Shuaiyang, Shao, Dongmei, Gong, Xuefeng, Huang, Guirui, Zhang, Shiyu, Zhang, Zhijie, Cui, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978578/
https://www.ncbi.nlm.nih.gov/pubmed/35386850
http://dx.doi.org/10.2147/DDDT.S349950