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The evolving biology of the proton‐coupled folate transporter: New insights into regulation, structure, and mechanism

The human proton‐coupled folate transporter (PCFT; SLC46A1) or hPCFT was identified in 2006 as the principal folate transporter involved in the intestinal absorption of dietary folates. A rare autosomal recessive hereditary folate malabsorption syndrome is attributable to human SLC46A1 variants. The...

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Detalles Bibliográficos
Autores principales: Hou, Zhanjun, Gangjee, Aleem, Matherly, Larry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978580/
https://www.ncbi.nlm.nih.gov/pubmed/35061292
http://dx.doi.org/10.1096/fj.202101704R