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A novel PRRX1 loss-of-function variation contributing to familial atrial fibrillation and congenital patent ductus arteriosus

Atrial fibrillation (AF) represents the most common type of sustained cardiac arrhythmia in humans and confers a significantly increased risk for thromboembolic stroke, congestive heart failure and premature death. Aggregating evidence emphasizes the predominant genetic defects underpinning AF and a...

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Detalles Bibliográficos
Autores principales: Ke, Zun-Ping, Zhang, Gao-Feng, Guo, Yu-Han, Sun, Yu-Min, Wang, Jun, Li, Ning, Qiu, Xing-Biao, Xu, Ying-Jia, Yang, Yi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978609/
https://www.ncbi.nlm.nih.gov/pubmed/35377386
http://dx.doi.org/10.1590/1678-4685-GMB-2021-0378