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Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children

BACKGROUND: Pediatric patients have significant interindividual variability in voriconazole exposure. The aim of the study was to identify factors associated with voriconazole concentrations and dose requirements to achieve therapeutic concentrations in pediatric patients. METHODS: Medical records o...

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Detalles Bibliográficos
Autores principales: Chen, Juan, Wu, Ying, He, Yuelin, Feng, Xiaoqin, Ren, Yuqiong, Liu, Shiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978631/
https://www.ncbi.nlm.nih.gov/pubmed/35386257
http://dx.doi.org/10.3389/fped.2022.846411