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Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome

Herpes simplex virus type 1 (HSV-1) is a highly prevalent virus in humans and causes severe forms of inflammation, such as herpes simplex encephalitis (HSE). Pyroptosis is a new inflammatory cell death triggered by inflammasome and cysteine-requiring aspartate protease-1 (caspase-1) activation. None...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Zeng, Qiongzhen, Xiao, Ji, Qin, Shurong, Wang, Yuan, Shan, Tianhao, Hu, Di, Zhu, Yexuan, Liu, Kaisheng, Zheng, Kai, Wang, Yifei, Ren, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978634/
https://www.ncbi.nlm.nih.gov/pubmed/35387080
http://dx.doi.org/10.3389/fmicb.2022.838808