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Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors

A series of hydrazone derivatives of 2-(benzamido) benzohydrazide was designed, synthesized, and characterized utilizing FTIR, NMR and UV spectroscopic techniques along with mass spectrometry. Compound 10 was also characterized through X-ray crystallography. These synthesized compounds were assessed...

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Detalles Bibliográficos
Autores principales: Kausar, Naghmana, Murtaza, Shahzad, Arshad, Muhammad Nadeem, Zaib Saleem, Rahman Shah, Asiri, Abdullah M., Kausar, Samia, Altaf, Ataf Ali, Tatheer, Adina, Elnaggar, Ashraf Y., El-Bahy, Salah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978638/
https://www.ncbi.nlm.nih.gov/pubmed/35424495
http://dx.doi.org/10.1039/d1ra07221h